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PGx Testing Could Benefit Seniors on Multiple Meds

PGx Testing Could Benefit Seniors on Multiple Meds
0 November 7, 2016

Researchers at Columbia University recently published research in Pharmacogenomics and Personalized Medicine indicating that pharmacogenetic (PGx) markers are a risk factor associated with frequent hospitalizations in older adults taking multiple medications. Finkelstein et al found that more than one major PGx variant was identified in half of cases of hospitalized adults. And though drug-gene interactions were identified in cases of hospitalizations, zero drug-gene interactions were identified in the control group of older adults taking multiple meds without hospitalization. As such, findings indicate that PGx testing may be beneficial to identify these drug-gene interactions in order to adjust drug or dose.

A nice overview of the study is available at ClinicalOmics.

Read the full text of Finkelstein et al “Pharmacogenetic polymorphism as an independent risk factor for frequent hospitalizations in older adults with polypharmacy: a pilot study” here.

Posted in Uncategorized by Rachel Mills